Targeting Epigenetics and Non-coding RNAs in Myocardial Infarction: From Mechanisms to Therapeutics

Chen, Jinhong and Liu, Zhichao and Ma, Li and Gao, Shengwei and Fu, Huanjie and Wang, Can and Lu, Anmin and Wang, Baohe and Gu, Xufang (2021) Targeting Epigenetics and Non-coding RNAs in Myocardial Infarction: From Mechanisms to Therapeutics. Frontiers in Genetics, 12. ISSN 1664-8021

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Official URL: https://doi.org/10.3389/fgene.2021.780649

Abstract

Myocardial infarction (MI) is a complicated pathology triggered by numerous environmental and genetic factors. Understanding the effect of epigenetic regulation mechanisms on the cardiovascular disease would advance the field and promote prophylactic methods targeting epigenetic mechanisms. Genetic screening guides individualised MI therapies and surveillance. The present review reported the latest development on the epigenetic regulation of MI in terms of DNA methylation, histone modifications, and microRNA-dependent MI mechanisms and the novel therapies based on epigenetics.

Item Type:	Article
Subjects:	STM Article > Medical Science
Depositing User:	Unnamed user with email support@stmarticle.org
Date Deposited:	12 Jan 2023 10:07
Last Modified:	02 May 2024 05:40
URI:	http://publish.journalgazett.co.in/id/eprint/41

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