Role of Pentraxin-3 in Periodontal Inflammation - A Comprehensive Review

Peeran, Syed Wali and Elhassan, Ahmed and Dawood, Tazeen and Ramalingam, Karthikeyan and Peeran, Syed Ali and Ahmed, Fatma and Adawi, Abdul-Aziz Ahmed A. (2021) Role of Pentraxin-3 in Periodontal Inflammation - A Comprehensive Review. Journal of Pharmaceutical Research International, 33 (55A). pp. 209-219. ISSN 2456-9119

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Official URL: https://doi.org/10.9734/jpri/2021/v33i55A33824

Abstract

Acute phase reactants like C-reactive protein (CRP), and pentraxin 3 (PTX3) are increased with inflammation and tissue injury. PTX3 is an acute phase protein and a member of the long pentraxin family. CRP is synthesized in the liver but PTX3 is generated locally at the inflammatory site. It is a fluid-phase pattern-recognition molecule that regulates antimicrobial immunity and inflammation by interfering with selectin-dependent neutrophil recruitment and regulating the complement cascade. Hence, PTX3 could be used as a potential biomarker to identify inflammatory response in both acute and chronic diseases. In this review, we discuss the role of PTX3 in periodontal inflammation.

Item Type:	Article
Subjects:	STM Article > Medical Science
Depositing User:	Unnamed user with email support@stmarticle.org
Date Deposited:	22 Feb 2023 07:56
Last Modified:	25 May 2024 08:33
URI:	http://publish.journalgazett.co.in/id/eprint/251

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