Effect of Leaf Essential Oil of Citrus sinensis on Haematological Parameters of Alloxan-induced Diabetic Rats

Soji-Omoniwa, O. and Muhammad, N. O. and Omoniwa, B. P. and Usman, L. A. (2014) Effect of Leaf Essential Oil of Citrus sinensis on Haematological Parameters of Alloxan-induced Diabetic Rats. International Blood Research & Reviews, 2 (3). pp. 113-120. ISSN 23217219

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Official URL: https://doi.org/10.9734/IBRR/2014/7952

Abstract

Aim: The aim of this study was to investigate the effect of leaf essential oil of Citrus sinensis (Rutaceae) on haematological parameters of alloxan – induced diabetic rats.

Methodology: Diabetes was induced in albino rats by intraperitoneal administration of single dose of alloxan monohydrate (150 mg/kg body weight). The leaf essential oil of Citrus sinensis at a dose of 110 mg/kg b.wt was administered every other day to the diabetic rats during 15 days. The effects of leaf essential oil on the erythrocyte and leucocyte indices were then evaluated.

Results: Red Blood Cell, Packed Cell Volume, White blood cell, Neutrophils and Leucocytes were reduced significantly in diabetic animals. However, treatment with leaf oil of C. sinensis increased these parameters subsequently.

Conclusion: It is concluded that leaf essential oil of Citrus sinensis improved the erythrocyte and leucocyte indices of diabetic rats.

Item Type:	Article
Subjects:	STM Article > Medical Science
Depositing User:	Unnamed user with email support@stmarticle.org
Date Deposited:	11 Jul 2023 04:30
Last Modified:	14 Mar 2024 04:54
URI:	http://publish.journalgazett.co.in/id/eprint/1542

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